Scientists May Have Discovered The Secret To Eternal Youth
It has been women’s and men’s fantasies for generations and now, ccording to experts, it is possible to reverse the aging process in human skin. Cambridge researchers have reprogrammed the skin cells of individuals aged 38 and 53 to make them appear up to 30 years younger.
The procedure reverses the aging process more effectively than earlier reprogramming techniques without causing cell damage. Researchers claim that they can even partially recover lost functionality in aged cells.
The researchers assert that while the research is still in its infancy, the discoveries might someday revolutionize regenerative medicine, especially if they can be duplicated in different cell types and bodily tissues.
De-aging has become quite popular in the last few years
Scientists have reprogrammed multiple mice, rat, and human cell types during the past decade in an effort to reverse cellular aging. But never before have so many years been removed from a cell’s age while preserving its kind and function.
The technique, developed by Diljeet Gill, a postdoctoral candidate at the Babraham Institute in Cambridge, and his colleagues, was published on April 8 in the journal eLife(opens in a new tab) under the name “maturation phase transient reprogramming.”
The researchers employed this approach to fibroblasts (a common kind of skin cell) from three middle-aged donors (average age: 50) and compared them to cells from younger donors (average age: 20 to 22). The researchers discovered that the middle-aged cells were chemically and genetically comparable to the younger ones. Further investigation revealed that the approach altered genes associated with age-related disorders like Alzheimer’s disease and cataracts.
Gill and his colleagues also examined the fibroblasts’ activity to discover if they might behave like younger skin cells. When they injured a layer of cells, they discovered that the rejuvenated cells moved quickly to fill the void, just as younger cells do when healing wounds.
Turning back time
Based on the Nobel Prize-winning procedure used to create stem cells, the new method circumvents the challenge of completely deleting cell identity by stopping reprogramming partway through the process. This enabled scientists to establish the optimal balance between reprogramming cells to make them biologically younger and regaining their specialized cell function.
Shinya Yamanaka was the first scientist to transform normal cells with a specified purpose into stem cells with the capacity to grow into any cell type 2007. Using four critical molecules known as the Yamanaka factors, stem cell reprogramming takes around 50 days. The new technique, termed “maturation phase transient reprogramming,” exposes cells to Yamanaka factors for only thirteen days. At this stage, age-related alterations are eliminated, and the cells momentarily lose their identity.
The partially reprogrammed skin cells were allowed to develop under normal settings to determine if their original function had reappeared. Analysis of the genome revealed that reprogrammed cells had recovered fibroblast-like characteristics, and collagen synthesis in the reprogrammed cells verified this.
Results of the study
The study’s findings were published in the life sciences journal eLife. The article said cosmetics are not the sole use for this new treatment. According to Babraham experts, this cellular treatment might be utilized to treat several medical ailments. As fresher cells create more collagen, the therapy might aid in the restoration of brittle bones, the healing of strained ligaments and tendons, the healing of skin lesions, and the structural repair of damaged tissue.
Cellular de-aging may potentially improve other age-related disorders. Alzheimer’s disease is linked to the APBA2 gene, revitalized by the MPTR epigenetic treatment. In addition, the MAF gene, which can cause cataracts, has shown improvement in response to the anti-aging medication.
More in Anti-Aging
Why Do You Have to Pay a Higher Health Insurance Premium?
Americans are spending an abysmal amount of money on healthcare each year. This includes high insurance premiums, co-pays, high deductibles, and...December 25, 2022
How To Maintain A healthy Body And Mind To Live A Happier Life
Happiness is a worthy objective, and it’s something you’ll need to pursue daily. Happiness is not something you acquire and then...December 19, 2022
Why opt for a Multi-year health care insurance policy?
People often neglect health care insurance policies, especially in Southeast Asian countries like India and Pakistan and other underdeveloped countries. They...December 15, 2022
This Is How You Can Keep Your Lips Young-Looking
Your lips are among the first places that display aging signs. Among some major changes in your lips, the lines circling...December 10, 2022
Makeup Hacks To Hide A Double Chin
Many consider a double chin not just a flaw but a mark on their face that ruins their perfect pictures and causes...December 8, 2022
How to Deal With Online Bullying and Anonymous Trolls?
Social media has revolutionized the world. While there have been several benefits of the same, there have been several cons. While...December 5, 2022
How To Prepare For Your Health Insurance Physical Examination
Before issuing health coverage, physical examinations are mandatory to assess an individual’s eligibility for who wants to buy a policy. People...November 30, 2022
Larvae with Anti-Aging Properties Discovered by a Turkish Scientist: An Astounding Discovery
The black soldier fly is used in various regions, from agribusiness to pet food. A Turkish teacher believes it will likewise...November 25, 2022
Your Positive Attitude Towards Aging Can Add 7.5 Years to Your Life
Age is just a number, and numerous stories and records are available to prove that being old is only from the...November 20, 2022
You must be logged in to post a comment Login