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The Strangest known Medical Conditions Known to Man

Diabetes, high blood pressure, heart diseases and respiratory illnesses are the most common diseases today. Some diseases come as a shock because they are not only unfamiliar but also peculiar. There is a need to know these diseases to discover whether you unknowingly have them. 

Here are some of the rarest diseases known to man:


People often try to mimic accents from foreign languages.  However, some people develop a condition of speaking in a foreign accent against their wish. Some of them do it even without interacting with people who speak the accent;  they can’t help it.

This disorder can be as a result of a stroke or an injury to the brain. The person with this disorder changes his or her tongue placement and the tone of voice. The only treatment for this syndrome is an extensive speech therapy to train the brain to speak in a certain way.

“I believe that illness has led me to a life of gratitude, so I consider my Lyme disease at this point in my life to be a blessing in disguise.” Rebecca Wells 


Cotard’s delusion is also referred to as ‘Walking Corpse Syndrome.’ It is a rare mental disorder in which a person believes that he or she is missing some body parts or that they are actually dead. People who have this disorder tend to spend most of their time in the cemetery and prefer to be among ‘their kind.’

Cotard’s delusion is associated with the dysfunction of the part of the brain that is responsible for recognizing faces. The dysfunction causes patients to feel detached emotionally and taken away from the sense of identifying themselves. There were certain treatments to the disorder, but the most effective one is the Electroconvulsive therapy (ECT).


This is a very weird condition where one’s rogue hand grasps things or moves against the wishes of the individual. It can be a rare side effect of severed corpus callosum after surgery or brain injury. A person with an alien hand syndrome has no control over the hand. Sadly, presently, there is no cure for this syndrome. However, it can be managed by keeping the hands busy. 


Also termed as ‘Stone Man Syndrome,’ this is a progressive genetic disorder that turns soft tissues into bones over time. A gene called ACVR1, which is found in the bones, tendons, muscles, and ligaments regulates the growth and development of those tissues.  ACVR1 is also responsible for turning cartilage into bones as children grow. Mutations in this gene can allow the ossification to go unchecked, turning skeletal muscles into bones and causing joints to fuse together. The prevalence of this condition is one in about over 2 million people. An attempt to remove the bone surgically results in the production of more bones in the area because trauma exacerbates the condition.


Cold Urticaria is also known as ‘cold allergy’. People with this condition need to be prepared for the coming winter. This is because they are allergic to cold air and water. They develop itches, and the condition could lead to extreme swelling of the throat and the tongue; it could actually be fatal. The condition is relieved with the help of antihistamines.


It is odd that one could be allergic to water given that a large portion of the human body comprises of water. People who suffer from this condition develop welts and hives after just minutes of exposure to water.  The cause of this condition is yet to be known. However, it is very rare. There are speculations that chemicals or impurities cause the allergy. The most common treatment is applying capsaicin to relieve pain.


Epidermodysplasia Verruciformis is also termed as the ‘Tree Man Syndrome’. People who have the condition have what appears to a tree bark growing on their skins. However, these are not tree barks but warts that are exacerbated by sun exposure.

The warts are caused by a rare mutation of EVER1/EVER2 genes, whose functions unclear. These gene mutations cause the skin to be susceptible to human papillomaviruses 5 and 8. The cause of worry is that there is no known cure for the condition; however, they symptoms are treatable. 

The next time you get unusual symptoms, please consult your doctor.  

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